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Thread: One Drug to Shrink All Tumors

  1. #1
    Join Date
    Jun 20 2005
    location, location

    One Drug to Shrink All Tumors

    A single drug can shrink or cure human breast, ovary, colon, bladder, brain, liver, and prostate tumors that have been transplanted into mice, researchers have found. The treatment, an antibody that blocks a "do not eat" signal normally displayed on tumor cells, coaxes the immune system to destroy the cancer cells.

    A decade ago, biologist Irving Weissman of the Stanford University School of Medicine in Palo Alto, California, discovered that leukemia cells produce higher levels of a protein called CD47 than do healthy cells. CD47, he and other scientists found, is also displayed on healthy blood cells; it's a marker that blocks the immune system from destroying them as they circulate. Cancers take advantage of this flag to trick the immune system into ignoring them. In the past few years, Weissman's lab showed that blocking CD47 with an antibody cured some cases of lymphomas and leukemias in mice by stimulating the immune system to recognize the cancer cells as invaders. Now, he and colleagues have shown that the CD47-blocking antibody may have a far wider impact than just blood cancers.

    "What we've shown is that CD47 isn't just important on leukemias and lymphomas," says Weissman. "It's on every single human primary tumor that we tested." Moreover, Weissman's lab found that cancer cells always had higher levels of CD47 than did healthy cells. How much CD47 a tumor made could predict the survival odds of a patient.

    Sounds promising. Hope they cure lung cancer before I get it.
    "All that stuff I was taught about evolution, embryology, Big Bang theory, all that is lies straight from the pit of hell [the bible] teaches us how to run all our public policy and everything in society." Rep. Paul Broun (R)

    "I hope I live to see the day when, as in the early days of our country, we won't have any public schools. The churches will have taken them over again and Christians will be running them. What a happy day that will be!" -- Jerry Falwell

  2. #2
    Join Date
    Sep 21 2001
    searching for intelligent
    How cool would that be?

    I represent the angry, gun toting meat eating people. ~ Denis Leary

    The same shepherd that protects the flock leads them to the slaughterhouse.

  3. #3
    Join Date
    Apr 02 2012
    Take apple cyder vinegar.

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